Principal Fluid Systems Engineer - Pharmaceutical Payloads

Employer description

About Varda

Low Earth orbit is open for business. Varda is accelerating the development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules. Varda’s W-Series vehicles are built, designed, and operated by Varda in-house, including the pharmaceutical processing payloads, the capsules, the C-PICA heat shields, and the satellite buses.

From life-saving pharmaceuticals to more powerful fiber optics, there is a world of products used on Earth today that can only be manufactured in space. Varda is accelerating innovation in the orbital economy by creating both the products and infrastructure needed so space can directly benefit life on Earth. Our mission is to expand the economic bounds of humankind.  

Our team is uniquely suited to accomplishing this goal, with leadership and staff comprised of veterans from SpaceX, Blue Origin, major pharmaceutical companies and Silicon Valley. Varda was founded in January 2021 by Will Bruey and Delian Asparouhov with significant backing from world class investors including Khosla Ventures, Lux Capital, Founders Fund, Caffeinated Capital, General Catalyst, and Also Capital.  

Varda is headquartered in El Segundo, California, where we have offices and a production facility where our vehicles, equipment, and materials are built, integrated, and tested. Varda also has offices in Washington, DC and Huntsville, AL. 

Join Varda, and work to create a bustling in-space ecosystem.

About this Role

As a Principal Fluid Systems Engineer on Varda's Payload team, you will define and lead the development of first-of-its-kind electromechanical fluid handling hardware that manufactures pharmaceuticals in microgravity, endures hypersonic reentry, and returns to Earth for material extraction. Your payloads will precisely meter, mix, filter, transport, and thermally control pharmaceutical materials in compact spacecraft-compatible hardware. You’ll shape the architecture and technical direction for pharmaceutical payloads—guiding project teams from requirements synthesis through development, on-orbit operation, recovery, and iteration for future missions.

You’ll collaborate closely with pharmaceutical scientists, process engineers, internal leadership, and spacecraft subsystem teams to translate mission objectives into qualified hardware that flies in months, not years. This role is ideal for engineers who combine deep mechanical and fluid systems expertise with the cross-functional breadth to define foundational in-space pharmaceutical manufacturing infrastructure.

Responsibilities

• Define requirements, architecture, and development plans for pharmaceutical manufacturing payloads
• Establish fluid system design standards for component selection and qualification, sealing, contamination control, thermal control, and verification/validation
• Lead project teams to develop of precision fluid systems incorporating valves, pumps, pistons, manifolds, tubing, fittings, seals, filters, sensors, and thermal control systems
• Drive system-level analyses, trade studies, and risk reduction using a variety of tools (hand calcs, Python/MATLAB models, FEA, etc. as needed)
• Lead build and test campaigns for prototypes and flight hardware to characterize performance and reliability
• Synthesize cross-functional inputs from business development, pharmaceutical science, process engineering, and spacecraft subsystem teams to develop requirements for new pharmaceutical payloads
• Develop standards for subsystem requirements, ICDs, verification plans, test reports, and recovery procedures
• Represent Varda in technical discussions with internal leadership, external partners, customers, and government stakeholders
• Lead continuous improvement and incorporation of lessons learned
• Mentor senior and entry-level engineers and shape best practices

Basic Qualifications

• BS/BEng in Mechanical, Aerospace, Mechatronics, Biomedical, Chemical, or related engineering discipline
• 7+ years of experience designing, integrating, testing, and troubleshooting electromechanical hardware
• Deep mechanical and fluid systems expertise with breadth in at least two adjacent disciplines such as avionics, software, thermal, optics, test, precision instrumentation, etc.
• Track record leading project teams through full-cycle electromechanical space flight hardware development
• Extensive experience with valves, pumps, pistons, tubing, manifolds, fittings, seals, filters, sensors, metering hardware, thermal-control hardware, and/or compact fluidic assemblies
• Excellent communication skills with customer, executive, and cross-disciplinary technical audiences

Preferred Skills and Experience

• 3+ years of cross-functional project leadership experience
• Prior full-cycle technical leadership of precision fluid-handling hardware for relevant applications
  • In Space: ECLSS, low-thrust propulsion, astronaut suits, spacecraft thermal control, etc.
  • On Earth: semiconductor process equipment, biotech process equipment, analytical instruments, medical devices, etc.
• Extensive experience planning and executing aerospace environmental testing (vibration, TVAC, EMI/EMC)
• Familiarity with microgravity fluid behavior, capillary-driven flows, gas/liquid separation, two-phase flow, cGMP principles, cleanroom practices, or regulated hardware environments

Pay Range

• Salary range: $181,913 - $232,444/per year
• This role is on-site in El Segundo, CA
• Leveling and base salary is determined by job-related skills, education level, experience level, and job performance
• You will be eligible for incentives in the form of stock options and/or long-term cash awards

Benefits

Consider your benefits covered for launch. At Varda, we invest in benefits and perks that support your health, financial well-being, and life beyond work. Benefits vary by position, with packages designed specifically for our regular full-time employees and interns. 

Regular Full-Time Positions: 

Health & Wellness  

• Flexible PTO policy + 12 paid holidays  

• 100% company-paid Medical, Dental, and Vision insurance plans for employees and dependents with FSA and employer-matched HSA options 

• Voluntary accident, hospital, critical illness, and pet insurance  

• $120/month wellness reimbursement for gym and fitness expenses  

• 12 weeks of parental leave (with supplemental disability leave for CA mothers)  

• Family building, pregnancy, parenting and menopause benefits via Maven Clinic  

• Sponsored One Medical memberships for employees and their dependents  

Financial & Retirement  

• Substantial incentive equity in a fully funded space start-up  

• 401(k) retirement plan with 6% employer match (immediately vested) 

• $20/pay period cell phone reimbursement  

• Relocation support for new hires, if needed  

Workplace Experience & Perks  

• Fully stocked kitchen with lunch provided daily and dinner provided twice weekly  

• Company and team-bonding events, happy hours and mission-success celebrations 

• Complimentary EV charging 

Benefits for Internship Positions: 

Health & Wellness   

• Paid observed holidays.   

• 100% company-paid Medical, Dental, and Vision insurance plans for employees and dependents with FSA and employer-matched HSA options.  

• $120/month wellness reimbursement for gym and fitness expenses.   

• Sponsored One Medical memberships for employees and their dependents.   

Financial   

• $20/pay period cell phone reimbursement.   

• Up to $4,000 gross up in relocation support, if eligible  

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